Paper Title
Postmortem Microbiome Dynamics: Systematic Review of Forensic Microbial Clock

Abstract
Post mortem interval in forensic science has many challenges like investigation, estimation, and the use of few physical and entomological markers. However, these methods offer benefits and a few cons, like environmental variability, temporal constraints. Microbial succession during decomposition, also known as the "microbial clock," has been the subject of a growing body of research in recent years as a new and possibly more accurate indicator of PMI.It is clear from a thorough examination of more than 30 peer-reviewed studies involving human cadavers and animal models that microbial communities experience internal and external changes that are predictable and time-dependent.Strong temporal correlations between microbial taxa and particular stages of decomposition have been shown in controlled studies employing murine and porcine models; some models predict PMI within a 2- to 3-day range over a period of weeks. Complementary studies on human cadavers demonstrate regular patterns of microbial succession in postmortem organs, exposing organ-specific microbial signatures that change over time and can be impacted by variables such as the cause of death, the environment, and the health of the individual. It can be used for quantitative analysis and also a biological technique to estimate time of death. But to understand and use its full potential, it needs to be studied more to its full potential using few data sets and various postmortem indicators such as entomological evidences. This review mainly focuses on summarizing already found knowledge about this clock and consider all the ecological and practical considerations that need to be made to make a perfect postmortem clock that can be used in forensic practices. Keywords - Postmortem Interval (PMI) Time Since Death, Forensic Taphonomy, Decomposition Stages, Forensic Entomology, Microbial Clock Thanatomicrobiome, Molecular Markers, Body Temperature Cooling, ForensicPathology, Advanced Imaging Techniques